Gene description for PYCRL
Gene name pyrroline-5-carboxylate reductase-like
Gene symbol PYCRL
Other names/aliases -
Species Bos taurus
 Database cross references - PYCRL
ExoCarta ExoCarta_512526
Vesiclepedia VP_512526
Entrez Gene 512526
UniProt Q58D08  
 PYCRL identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PYCRL
Molecular Function
    pyrroline-5-carboxylate reductase activity GO:0004735 IEA
Biological Process
    L-proline biosynthetic process GO:0055129 IEA
 Experiment description of studies that identified PYCRL in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PYCRL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PYCRL is involved
PathwayEvidenceSource
Glutamate and glutamine metabolism IEA Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome





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