Gene description for PKM
Gene name pyruvate kinase, muscle
Gene symbol PKM
Other names/aliases -
Species Bos taurus
 Database cross references - PKM
ExoCarta ExoCarta_512571
Vesiclepedia VP_512571
Entrez Gene 512571
 PKM identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PKM
Molecular Function
    magnesium ion binding GO:0000287 IEA
    pyruvate kinase activity GO:0004743 IEA
    potassium ion binding GO:0030955 IEA
Biological Process
    glycolytic process GO:0006096 IEA
    cellular response to insulin stimulus GO:0032869 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PKM in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PKM
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PKM is involved
No pathways found





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