Gene description for PNPO
Gene name pyridoxamine 5'-phosphate oxidase
Gene symbol PNPO
Other names/aliases -
Species Bos taurus
 Database cross references - PNPO
ExoCarta ExoCarta_512573
Entrez Gene 512573
UniProt Q5E9K3  
 PNPO identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PNPO
Molecular Function
    FMN binding GO:0010181 IEA
    pyridoxamine-phosphate oxidase activity GO:0004733 IBA
Biological Process
    pyridoxine biosynthetic process GO:0008615 IEA
    oxidation-reduction process GO:0055114 IEA
    pyridoxal phosphate biosynthetic process GO:0042823 IBA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified PNPO in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PNPO
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PNPO is involved
Vitamins B6 activation to pyridoxal phosphate IEA Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here