Gene description for COPS6
Gene name COP9 signalosome subunit 6
Gene symbol COPS6
Other names/aliases -
Species Bos taurus
 Database cross references - COPS6
ExoCarta ExoCarta_512756
Vesiclepedia VP_512756
Entrez Gene 512756
UniProt A6QQ21  
 COPS6 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COPS6
Molecular Function
    protein binding GO:0005515 IEA
    metallopeptidase activity GO:0008237 IEA
Biological Process
    protein deneddylation GO:0000338 IEA
Subcellular Localization
    COP9 signalosome GO:0008180 IEA
 Experiment description of studies that identified COPS6 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COPS6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COPS6 is involved
No pathways found





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