Gene description for ACO1
Gene name aconitase 1, soluble
Gene symbol ACO1
Other names/aliases -
Species Bos taurus
 Database cross references - ACO1
ExoCarta ExoCarta_512995
Entrez Gene 512995
UniProt Q0VCU1  
 ACO1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ACO1
Molecular Function
    4 iron, 4 sulfur cluster binding GO:0051539 ISS
    iron-responsive element binding GO:0030350 ISS
    metal ion binding GO:0046872 IEA
    aconitate hydratase activity GO:0003994 ISS
Biological Process
    response to iron(II) ion GO:0010040 ISS
    cellular iron ion homeostasis GO:0006879 IEA
    tricarboxylic acid cycle GO:0006099 IEA
    citrate metabolic process GO:0006101 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified ACO1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ACO1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ACO1 is involved
No pathways found





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