Gene description for PLSCR1
Gene name phospholipid scramblase 1
Gene symbol PLSCR1
Other names/aliases PLSCR2
Species Bos taurus
 Database cross references - PLSCR1
ExoCarta ExoCarta_513193
Entrez Gene 513193
UniProt Q3ZBG9  
 PLSCR1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PLSCR1
Molecular Function
    metal ion binding GO:0046872 IEA
    phospholipid scramblase activity GO:0017128 IBA
Biological Process
    phospholipid scrambling GO:0017121 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified PLSCR1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PLSCR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLSCR1 is involved
No pathways found

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