Gene description for FBP1
Gene name fructose-1,6-bisphosphatase 1
Gene symbol FBP1
Other names/aliases -
Species Bos taurus
 Database cross references - FBP1
ExoCarta ExoCarta_513483
Entrez Gene 513483
UniProt Q3SZB7  
 FBP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FBP1
Molecular Function
    fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 ISS
    metal ion binding GO:0046872 ISS
    identical protein binding GO:0042802 IEA
    AMP binding GO:0016208 ISS
    monosaccharide binding GO:0048029 ISS
Biological Process
    negative regulation of glycolytic process GO:0045820 ISS
    cellular response to magnesium ion GO:0071286 ISS
    regulation of gluconeogenesis GO:0006111 ISS
    gluconeogenesis GO:0006094 ISS
    dephosphorylation GO:0016311 ISS
    fructose 6-phosphate metabolic process GO:0006002 ISS
    protein homotetramerization GO:0051289 ISS
    cellular response to drug GO:0035690 ISS
    negative regulation of cell growth GO:0030308 ISS
    negative regulation of Ras protein signal transduction GO:0046580 ISS
Subcellular Localization
    cytosol GO:0005829 ISS
    cytoplasm GO:0005737 ISS
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified FBP1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FBP1 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome





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