Gene description for GSDMD
Gene name gasdermin D
Gene symbol GSDMD
Other names/aliases GSDMDC1
Species Bos taurus
 Database cross references - GSDMD
ExoCarta ExoCarta_513939
Vesiclepedia VP_513939
Entrez Gene 513939
 GSDMD identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GSDMD
Molecular Function
    phosphatidylserine binding GO:0001786 IEA
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IEA
    phosphatidylinositol-4-phosphate binding GO:0070273 IEA
Biological Process
    defense response to bacterium GO:0042742 IEA
    pyroptotic inflammatory response GO:0070269 IEA
Subcellular Localization
    NLRP3 inflammasome complex GO:0072559 IEA
 Experiment description of studies that identified GSDMD in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GSDMD
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GSDMD is involved
No pathways found





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