Gene description for SNX5
Gene name sorting nexin 5
Gene symbol SNX5
Other names/aliases -
Species Bos taurus
 Database cross references - SNX5
ExoCarta ExoCarta_514423
Entrez Gene 514423
UniProt Q3ZBM5  
 SNX5 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SNX5
Molecular Function
    phosphatidylinositol binding GO:0035091 ISS
Biological Process
    pinocytosis GO:0006907 ISS
    intracellular protein transport GO:0006886 IEA
    endocytosis GO:0006897 IBA
    vesicle organization GO:0016050 IBA
Subcellular Localization
    ruffle GO:0001726 IEA
    early endosome membrane GO:0031901 ISS
    macropinocytic cup GO:0070685 ISS
    endosome GO:0005768 IBA
    cytoplasmic vesicle membrane GO:0030659 IEA
    phagocytic cup GO:0001891 IEA
    extrinsic component of membrane GO:0019898 IBA
    extrinsic component of cytoplasmic side of plasma membrane GO:0031234 ISS
    extrinsic component of endosome membrane GO:0031313 ISS
 Experiment description of studies that identified SNX5 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SNX5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SNX5 is involved
PathwayEvidenceSource
Golgi Associated Vesicle Biogenesis IEA Reactome





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