Gene description for PPP2R4
Gene name protein phosphatase 2A activator, regulatory subunit 4
Gene symbol PPP2R4
Other names/aliases -
Species Bos taurus
 Database cross references - PPP2R4
ExoCarta ExoCarta_514460
Vesiclepedia VP_514460
Entrez Gene 514460
UniProt Q2KJ44  
 PPP2R4 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PPP2R4
Molecular Function
    peptidyl-prolyl cis-trans isomerase activity GO:0003755 IEA
    protein tyrosine phosphatase activator activity GO:0008160 IEA
Biological Process
    mitotic spindle organization GO:0007052 IEA
Subcellular Localization
    protein phosphatase type 2A complex GO:0000159 IEA
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PPP2R4 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPP2R4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PPP2R4 is involved
No pathways found





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