Gene description for RAB13
Gene name RAB13, member RAS oncogene family
Gene symbol RAB13
Other names/aliases -
Species Bos taurus
 Database cross references - RAB13
ExoCarta ExoCarta_514541
Entrez Gene 514541
UniProt Q58DS5  
 RAB13 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB13
Molecular Function
    GTP binding GO:0005525 ISS
Biological Process
    bicellular tight junction assembly GO:0070830 ISS
    trans-Golgi network to recycling endosome transport GO:0044795 ISS
    protein transport GO:0015031 IEA
    establishment of Sertoli cell barrier GO:0097368 ISS
    protein localization to cell leading edge GO:1902463 ISS
    small GTPase mediated signal transduction GO:0007264 IEA
    cellular response to insulin stimulus GO:0032869 ISS
    endocytic recycling GO:0032456 ISS
    establishment of protein localization to plasma membrane GO:0090002 ISS
    cortical actin cytoskeleton organization GO:0030866 ISS
    endosomal transport GO:0016197 ISS
    endothelial cell chemotaxis GO:0035767 ISS
    neuron projection development GO:0031175 ISS
    protein kinase A signaling GO:0010737 ISS
Subcellular Localization
    lateral plasma membrane GO:0016328 ISS
    extracellular exosome GO:0070062 IEA
    recycling endosome membrane GO:0055038 IEA
    endocytic vesicle GO:0030139 ISS
    neuron projection GO:0043005 ISS
    recycling endosome GO:0055037 ISS
    lamellipodium GO:0030027 ISS
    insulin-responsive compartment GO:0032593 ISS
    transport vesicle membrane GO:0030658 IEA
    plasma membrane GO:0005886 ISS
    trans-Golgi network GO:0005802 ISS
    bicellular tight junction GO:0005923 ISS
    cytoplasmic vesicle GO:0031410 ISS
 Experiment description of studies that identified RAB13 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAB13 is involved
PathwayEvidenceSource
Translocation of GLUT4 to the plasma membrane IEA Reactome





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