Gene description for DBNL
Gene name drebrin-like
Gene symbol DBNL
Other names/aliases -
Species Bos taurus
 Database cross references - DBNL
ExoCarta ExoCarta_514706
Entrez Gene 514706
UniProt A6H7G2  
 DBNL identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DBNL
Molecular Function
    actin filament binding GO:0051015 ISS
    protein domain specific binding GO:0019904 IEA
Biological Process
    neuron projection morphogenesis GO:0048812 ISS
    podosome assembly GO:0071800 ISS
    receptor-mediated endocytosis GO:0006898 IEA
    Rac protein signal transduction GO:0016601 IEA
    synapse assembly GO:0007416 ISS
    immune system process GO:0002376 IEA
    ruffle assembly GO:0097178 IEA
Subcellular Localization
    ruffle GO:0001726 ISS
    plasma membrane GO:0005886 IEA
    lamellipodium GO:0030027 ISS
    podosome GO:0002102 ISS
    cell junction GO:0030054 IEA
    cell cortex GO:0005938 IEA
    synapse GO:0045202 IEA
    cytosol GO:0005829 IEA
    Golgi membrane GO:0000139 IEA
    extracellular exosome GO:0070062 IEA
    clathrin-coated vesicle membrane GO:0030665 IEA
 Experiment description of studies that identified DBNL in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DBNL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DBNL is involved
PathwayEvidenceSource
Caspase-mediated cleavage of cytoskeletal proteins IEA Reactome





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