Gene description for RAD51
Gene name RAD51 recombinase
Gene symbol RAD51
Other names/aliases -
Species Bos taurus
 Database cross references - RAD51
ExoCarta ExoCarta_514749
Entrez Gene 514749
UniProt Q2KJ94  
 RAD51 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAD51
Molecular Function
    identical protein binding GO:0042802 IEA
    double-stranded DNA binding GO:0003690 IEA
    ATP binding GO:0005524 IEA
    protein C-terminus binding GO:0008022 IEA
    damaged DNA binding GO:0003684 IEA
    DNA polymerase binding GO:0070182 IEA
    single-stranded DNA-dependent ATPase activity GO:0043142 IEA
Biological Process
    DNA unwinding involved in DNA replication GO:0006268 IEA
    regulation of double-strand break repair via homologous recombination GO:0010569 ISS
    cellular response to camptothecin GO:0072757 ISS
    cellular response to ionizing radiation GO:0071479 ISS
    double-strand break repair via homologous recombination GO:0000724 ISS
    cellular response to DNA damage stimulus GO:0006974 ISS
    meiotic nuclear division GO:0007126 IEA
    protein homooligomerization GO:0051260 IEA
    positive regulation of DNA ligation GO:0051106 IEA
Subcellular Localization
    nucleus GO:0005634 ISS
    mitochondrial matrix GO:0005759 IEA
    microtubule organizing center GO:0005815 IEA
    PML body GO:0016605 IEA
    cytoplasm GO:0005737 ISS
    nuclear chromosome GO:0000228 ISS
    nucleolus GO:0005730 IEA
    lateral element GO:0000800 IEA
    perinuclear region of cytoplasm GO:0048471 ISS
 Experiment description of studies that identified RAD51 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAD51
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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