Gene description for BIN2
Gene name bridging integrator 2
Gene symbol BIN2
Other names/aliases -
Species Bos taurus
 Database cross references - BIN2
ExoCarta ExoCarta_515025
Vesiclepedia VP_515025
Entrez Gene 515025
 BIN2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for BIN2
Molecular Function
    protein binding GO:0005515 IEA
    phospholipid binding GO:0005543 IEA
Biological Process
    phagocytosis, engulfment GO:0006911 IEA
    podosome assembly GO:0071800 IEA
    plasma membrane tubulation GO:0097320 IEA
Subcellular Localization
    phagocytic cup GO:0001891 IEA
    podosome GO:0002102 IEA
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified BIN2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for BIN2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which BIN2 is involved
No pathways found





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