Gene description for RAP2C
Gene name RAP2C, member of RAS oncogene family
Gene symbol RAP2C
Other names/aliases -
Species Bos taurus
 Database cross references - RAP2C
ExoCarta ExoCarta_515181
Entrez Gene 515181
UniProt Q08DI5  
 RAP2C identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAP2C
Molecular Function
    GTP binding GO:0005525 IEA
    transcription coactivator activity GO:0003713 IEA
    GDP binding GO:0019003 IEA
Biological Process
    negative regulation of cell migration GO:0030336 ISS
    regulation of nucleic acid-templated transcription GO:1903506 IEA
    regulation of protein tyrosine kinase activity GO:0061097 ISS
    positive regulation of protein autophosphorylation GO:0031954 ISS
    establishment of endothelial intestinal barrier GO:0090557 IEA
    Rap protein signal transduction GO:0032486 ISS
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    bicellular tight junction GO:0005923 IEA
    recycling endosome membrane GO:0055038 ISS
    cytosol GO:0005829 IEA
    plasma membrane GO:0005886 IEA
    cell-cell contact zone GO:0044291 IEA
 Experiment description of studies that identified RAP2C in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAP2C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAP2C is involved
No pathways found

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