Gene description for RAP2C
Gene name RAP2C, member of RAS oncogene family
Gene symbol RAP2C
Other names/aliases -
Species Bos taurus
 Database cross references - RAP2C
ExoCarta ExoCarta_515181
Vesiclepedia VP_515181
Entrez Gene 515181
UniProt Q08DI5  
 RAP2C identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAP2C
Molecular Function
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 IEA
    GDP binding GO:0019003 IEA
Biological Process
    negative regulation of cell migration GO:0030336 IEA
    Rap protein signal transduction GO:0032486 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified RAP2C in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAP2C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAP2C is involved
PathwayEvidenceSource
Immune System IEA Reactome
Innate Immune System IEA Reactome
Neutrophil degranulation IEA Reactome





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