Gene description for SPICE1
Gene name spindle and centriole associated protein 1
Gene symbol SPICE1
Other names/aliases CCDC52
Species Bos taurus
 Database cross references - SPICE1
ExoCarta ExoCarta_515350
Vesiclepedia VP_515350
Entrez Gene 515350
UniProt Q2T9X8  
 SPICE1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SPICE1
Biological Process
    regulation of centriole replication GO:0046599 IEA
    metaphase chromosome alignment GO:0051310 IEA
    mitotic spindle assembly GO:0090307 IEA
Subcellular Localization
    centrosome GO:0005813 IEA
    centriole GO:0005814 IEA
    spindle GO:0005819 IEA
 Experiment description of studies that identified SPICE1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SPICE1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SPICE1 is involved
No pathways found





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