Gene description for PLCB3
Gene name phospholipase C, beta 3 (phosphatidylinositol-specific)
Gene symbol PLCB3
Other names/aliases -
Species Bos taurus
 Database cross references - PLCB3
ExoCarta ExoCarta_515669
Vesiclepedia VP_515669
Entrez Gene 515669
 PLCB3 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PLCB3
Molecular Function
    phosphatidylinositol phospholipase C activity GO:0004435 IEA
    calcium ion binding GO:0005509 IEA
    calmodulin binding GO:0005516 IEA
Biological Process
    lipid catabolic process GO:0016042 IEA
    phosphatidylinositol-mediated signaling GO:0048015 IEA
 Experiment description of studies that identified PLCB3 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PLCB3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLCB3 is involved
No pathways found





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