Gene description for FGR
Gene name FGR proto-oncogene, Src family tyrosine kinase
Gene symbol FGR
Other names/aliases -
Species Bos taurus
 Database cross references - FGR
ExoCarta ExoCarta_516133
Vesiclepedia VP_516133
Entrez Gene 516133
 FGR identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FGR
Molecular Function
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA
    signaling receptor binding GO:0005102 IEA
    ATP binding GO:0005524 IEA
Biological Process
    protein phosphorylation GO:0006468 IEA
    cell surface receptor protein tyrosine kinase signaling pathway GO:0007169 IEA
    integrin-mediated signaling pathway GO:0007229 IEA
    cell differentiation GO:0030154 IEA
    innate immune response GO:0045087 IEA
Subcellular Localization
    extrinsic component of cytoplasmic side of plasma membrane GO:0031234 IEA
 Experiment description of studies that identified FGR in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FGR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FGR is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here