Gene description for UCHL3
Gene name ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Gene symbol UCHL3
Other names/aliases -
Species Bos taurus
 Database cross references - UCHL3
ExoCarta ExoCarta_520170
Vesiclepedia VP_520170
Entrez Gene 520170
UniProt Q2TBG8  
 UCHL3 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for UCHL3
Molecular Function
    cysteine-type deubiquitinase activity GO:0004843 IEA
Biological Process
    ubiquitin-dependent protein catabolic process GO:0006511 IEA
    protein deubiquitination GO:0016579 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified UCHL3 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UCHL3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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