Gene description for UCHL3
Gene name ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Gene symbol UCHL3
Other names/aliases -
Species Bos taurus
 Database cross references - UCHL3
ExoCarta ExoCarta_520170
Entrez Gene 520170
UniProt Q2TBG8  
 UCHL3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for UCHL3
Molecular Function
    ubiquitin-specific protease activity GO:0004843 IBA
    ubiquitin binding GO:0043130 IEA
Biological Process
    protein deubiquitination GO:0016579 IBA
    ubiquitin-dependent protein catabolic process GO:0006511 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IBA
    nucleoplasm GO:0005654 IEA
 Experiment description of studies that identified UCHL3 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UCHL3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which UCHL3 is involved
No pathways found





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