Gene description for SPAST
Gene name spastin
Gene symbol SPAST
Other names/aliases SPG4
Species Bos taurus
 Database cross references - SPAST
ExoCarta ExoCarta_521442
Vesiclepedia VP_521442
Entrez Gene 521442
UniProt A2VDN5  
 SPAST identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SPAST
Molecular Function
    ATP binding GO:0005524 IEA
    microtubule severing ATPase activity GO:0008568 IEA
    ATP hydrolysis activity GO:0016887 IEA
Subcellular Localization
    microtubule cytoskeleton GO:0015630 IEA
 Experiment description of studies that identified SPAST in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SPAST
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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