Gene description for VPS35
Gene name vacuolar protein sorting 35 homolog (S. cerevisiae)
Gene symbol VPS35
Other names/aliases -
Species Bos taurus
 Database cross references - VPS35
ExoCarta ExoCarta_521864
Vesiclepedia VP_521864
Entrez Gene 521864
UniProt Q2HJG5  
 VPS35 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for VPS35
Biological Process
    intracellular protein transport GO:0006886 IEA
    retrograde transport, endosome to Golgi GO:0042147 IEA
Subcellular Localization
    late endosome GO:0005770 IEA
    retromer complex GO:0030904 IEA
    retromer, cargo-selective complex GO:0030906 IEA
 Experiment description of studies that identified VPS35 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VPS35
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VPS35 is involved
PathwayEvidenceSource
Signal Transduction IEA Reactome
Signaling by WNT IEA Reactome
WNT ligand biogenesis and trafficking IEA Reactome





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