Gene description for FGA
Gene name fibrinogen alpha chain
Gene symbol FGA
Other names/aliases -
Species Bos taurus
 Database cross references - FGA
ExoCarta ExoCarta_522039
Vesiclepedia VP_522039
Entrez Gene 522039
UniProt P02672  
 FGA identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for FGA
Molecular Function
    protein binding, bridging GO:0030674 IEA
    receptor binding GO:0005102 IEA
Biological Process
    platelet activation GO:0030168 IEA
    innate immune response GO:0045087 IEA
    protein polymerization GO:0051258 IEA
    signal transduction GO:0007165 IEA
Subcellular Localization
    fibrinogen complex GO:0005577 IEA
 Experiment description of studies that identified FGA in exosomes
1
Experiment ID 187
MISEV standards
EM
EV Biophysical techniques
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FGA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FGA is involved
No pathways found





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