Gene description for GPD1
Gene name glycerol-3-phosphate dehydrogenase 1 (soluble)
Gene symbol GPD1
Other names/aliases -
Species Bos taurus
 Database cross references - GPD1
ExoCarta ExoCarta_525042
Entrez Gene 525042
UniProt Q5EA88  
 GPD1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GPD1
Molecular Function
    glycerol-3-phosphate dehydrogenase activity GO:0004368 ISS
    NAD binding GO:0051287 IEA
    glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367 IEA
    protein homodimerization activity GO:0042803 IEA
Biological Process
    carbohydrate metabolic process GO:0005975 ISS
    positive regulation of glycolytic process GO:0045821 IEA
    gluconeogenesis GO:0006094 ISS
    cellular response to tumor necrosis factor GO:0071356 IEA
    glycerol-3-phosphate catabolic process GO:0046168 IEA
    cellular response to cAMP GO:0071320 IEA
    glycerol-3-phosphate metabolic process GO:0006072 ISS
    glycerophosphate shuttle GO:0006127 IEA
Subcellular Localization
    glycerol-3-phosphate dehydrogenase complex GO:0009331 IEA
    extracellular exosome GO:0070062 IEA
    mitochondrion GO:0005739 IEA
    cytosol GO:0005829 ISS
 Experiment description of studies that identified GPD1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GPD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GPD1 is involved
PathwayEvidenceSource
Synthesis of PA IEA Reactome
Triglyceride Biosynthesis IEA Reactome





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