Gene description for GSS
Gene name glutathione synthetase
Gene symbol GSS
Other names/aliases -
Species Bos taurus
 Database cross references - GSS
ExoCarta ExoCarta_525059
Entrez Gene 525059
UniProt Q5EAC2  
 GSS identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GSS
Molecular Function
    magnesium ion binding GO:0000287 ISS
    protein homodimerization activity GO:0042803 ISS
    glutathione synthase activity GO:0004363 IEA
    ATP binding GO:0005524 ISS
    glutathione binding GO:0043295 ISS
Biological Process
    response to cadmium ion GO:0046686 IEA
    glutathione biosynthetic process GO:0006750 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified GSS in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GSS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GSS is involved
Glutathione synthesis and recycling IEA Reactome

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