Gene description for GSS
Gene name glutathione synthetase
Gene symbol GSS
Other names/aliases -
Species Bos taurus
 Database cross references - GSS
ExoCarta ExoCarta_525059
Entrez Gene 525059
UniProt Q5EAC2  
 GSS identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GSS
Molecular Function
    magnesium ion binding GO:0000287 ISS
    protein homodimerization activity GO:0042803 ISS
    glutathione synthase activity GO:0004363 IEA
    ATP binding GO:0005524 ISS
    glutathione binding GO:0043295 ISS
Biological Process
    response to cadmium ion GO:0046686 IEA
    glutathione biosynthetic process GO:0006750 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified GSS in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GSS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GSS is involved
PathwayEvidenceSource
Glutathione synthesis and recycling IEA Reactome





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