Gene description for FERMT3
Gene name fermitin family member 3
Gene symbol FERMT3
Other names/aliases URP2
Species Bos taurus
 Database cross references - FERMT3
ExoCarta ExoCarta_525159
Entrez Gene 525159
UniProt Q32LP0  
 FERMT3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for FERMT3
Molecular Function
    integrin binding GO:0005178 ISS
Biological Process
    integrin activation GO:0033622 ISS
    leukocyte cell-cell adhesion GO:0007159 ISS
    regulation of cell-cell adhesion mediated by integrin GO:0033632 ISS
    platelet aggregation GO:0070527 ISS
Subcellular Localization
    cell projection GO:0042995 IEA
    cell junction GO:0030054 IEA
    podosome GO:0002102 ISS
 Experiment description of studies that identified FERMT3 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FERMT3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FERMT3 is involved
No pathways found





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