Gene description for S100B
Gene name S100 calcium binding protein B
Gene symbol S100B
Other names/aliases -
Species Bos taurus
 Database cross references - S100B
ExoCarta ExoCarta_525716
Entrez Gene 525716
UniProt P02638  
 S100B identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for S100B
Molecular Function
    protein homodimerization activity GO:0042803 ISS
    zinc ion binding GO:0008270 IDA
    calcium-dependent protein binding GO:0048306 IEA
    kinase inhibitor activity GO:0019210 NAS
    S100 protein binding GO:0044548 ISS
    calcium ion binding GO:0005509 IDA
    tau protein binding GO:0048156 IPI
    RAGE receptor binding GO:0050786 IEA
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of complement activation GO:0045917 NAS
    regulation of neuronal synaptic plasticity GO:0048168 IEA
    axonogenesis GO:0007409 NAS
    learning or memory GO:0007611 ISS
    regulation of translation GO:0006417 NAS
    phosphorylation GO:0016310 NAS
    negative regulation of phosphorylation GO:0042326 NAS
    memory GO:0007613 IEA
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IEA
    astrocyte activation GO:0048143 NAS
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IEA
    ruffle GO:0001726 IEA
    neuronal cell body GO:0043025 IEA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified S100B in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for S100B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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