Gene description for TPP2
Gene name tripeptidyl peptidase II
Gene symbol TPP2
Other names/aliases TPP-2
Species Bos taurus
 Database cross references - TPP2
ExoCarta ExoCarta_526052
Entrez Gene 526052
UniProt A5PK39  
 TPP2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TPP2
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
    aminopeptidase activity GO:0004177 IEA
Biological Process
    proteolysis GO:0006508 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified TPP2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TPP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TPP2 is involved
No pathways found





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