Gene description for DCTN2
Gene name dynactin 2 (p50)
Gene symbol DCTN2
Other names/aliases -
Species Bos taurus
 Database cross references - DCTN2
ExoCarta ExoCarta_527201
Entrez Gene 527201
UniProt Q3ZCF0  
 DCTN2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DCTN2
Molecular Function
    spectrin binding GO:0030507 IEA
    motor activity GO:0003774 IEA
Biological Process
    mitotic spindle organization GO:0007052 IBA
    cell proliferation GO:0008283 IEA
    mitotic nuclear division GO:0007067 IEA
    melanosome transport GO:0032402 IEA
    metabolic process GO:0008152 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    dynactin complex GO:0005869 IBA
    vesicle GO:0031982 ISS
    cytoplasm GO:0005737 IBA
    kinetochore GO:0000776 IEA
    microtubule GO:0005874 IEA
    dynein complex GO:0030286 IEA
    growth cone GO:0030426 IEA
    extracellular exosome GO:0070062 IEA
    centrosome GO:0005813 IBA
 Experiment description of studies that identified DCTN2 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DCTN2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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