Gene description for DCTN2
Gene name dynactin 2 (p50)
Gene symbol DCTN2
Other names/aliases -
Species Bos taurus
 Database cross references - DCTN2
ExoCarta ExoCarta_527201
Entrez Gene 527201
UniProt Q3ZCF0  
 DCTN2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DCTN2
Molecular Function
    spectrin binding GO:0030507 IEA
    motor activity GO:0003774 IEA
Biological Process
    mitotic spindle organization GO:0007052 IBA
    cell proliferation GO:0008283 IEA
    mitotic nuclear division GO:0007067 IEA
    melanosome transport GO:0032402 IEA
    metabolic process GO:0008152 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    dynactin complex GO:0005869 IBA
    vesicle GO:0031982 ISS
    cytoplasm GO:0005737 IBA
    kinetochore GO:0000776 IEA
    microtubule GO:0005874 IEA
    dynein complex GO:0030286 IEA
    growth cone GO:0030426 IEA
    extracellular exosome GO:0070062 IEA
    centrosome GO:0005813 IBA
 Experiment description of studies that identified DCTN2 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DCTN2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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