Gene description for HNRNPK
Gene name heterogeneous nuclear ribonucleoprotein K
Gene symbol HNRNPK
Other names/aliases HNRPK
Species Bos taurus
 Database cross references - HNRNPK
ExoCarta ExoCarta_528135
Entrez Gene 528135
UniProt Q3T0D0  
 HNRNPK identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HNRNPK
Molecular Function
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IEA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0001077 IEA
    poly(A) RNA binding GO:0044822 IEA
Biological Process
    regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter GO:0072369 IEA
    regulation of low-density lipoprotein particle clearance GO:0010988 IEA
    RNA splicing GO:0008380 IEA
    mRNA processing GO:0006397 IEA
    transcription, DNA-templated GO:0006351 IEA
    positive regulation of receptor-mediated endocytosis GO:0048260 IEA
    positive regulation of low-density lipoprotein particle receptor biosynthetic process GO:0045716 IEA
Subcellular Localization
    podosome GO:0002102 IEA
    extracellular exosome GO:0070062 IEA
    membrane GO:0016020 IEA
    nuclear chromatin GO:0000790 IEA
    cell projection GO:0042995 IEA
    catalytic step 2 spliceosome GO:0071013 IEA
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 IEA
    focal adhesion GO:0005925 IEA
 Experiment description of studies that identified HNRNPK in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HNRNPK
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HNRNPK is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA IEA Reactome





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