Gene description for ENPP3
Gene name ectonucleotide pyrophosphatase/phosphodiesterase 3
Gene symbol ENPP3
Other names/aliases -
Species Bos taurus
 Database cross references - ENPP3
ExoCarta ExoCarta_529405
Entrez Gene 529405
UniProt P15396  
 ENPP3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ENPP3
Molecular Function
    NADH pyrophosphatase activity GO:0035529 IEA
    nucleic acid binding GO:0003676 IEA
    polysaccharide binding GO:0030247 IEA
    metal ion binding GO:0046872 IEA
    phosphodiesterase I activity GO:0004528 IEA
    scavenger receptor activity GO:0005044 IEA
Biological Process
    immune response GO:0006955 IEA
    receptor-mediated endocytosis GO:0006898 IEA
    nucleic acid phosphodiester bond hydrolysis GO:0090305 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified ENPP3 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ENPP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ENPP3 is involved
No pathways found

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