Gene description for TMED10
Gene name transmembrane emp24-like trafficking protein 10 (yeast)
Gene symbol TMED10
Other names/aliases TMP21
Species Bos taurus
 Database cross references - TMED10
ExoCarta ExoCarta_529761
Entrez Gene 529761
UniProt Q5E971  
 TMED10 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TMED10
Biological Process
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 ISS
    regulation of beta-amyloid formation GO:1902003 ISS
    protein transport GO:0015031 IEA
    COPI-coated vesicle budding GO:0035964 ISS
Subcellular Localization
    melanosome GO:0042470 IEA
    COPI-coated vesicle GO:0030137 ISS
    plasma membrane GO:0005886 ISS
    endoplasmic reticulum membrane GO:0005789 IEA
    trans-Golgi network transport vesicle GO:0030140 ISS
    endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116 IEA
    secretory granule membrane GO:0030667 ISS
    gamma-secretase complex GO:0070765 ISS
    integral component of membrane GO:0016021 IEA
    transport vesicle membrane GO:0030658 IEA
    Golgi membrane GO:0000139 ISS
 Experiment description of studies that identified TMED10 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TMED10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TMED10 is involved
No pathways found

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