Gene description for PCBD1
Gene name pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
Gene symbol PCBD1
Other names/aliases DCoH
Species Bos taurus
 Database cross references - PCBD1
ExoCarta ExoCarta_530736
Entrez Gene 530736
UniProt Q3ZBD3  
 PCBD1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PCBD1
Molecular Function
    4-alpha-hydroxytetrahydrobiopterin dehydratase activity GO:0008124 IEA
    phenylalanine 4-monooxygenase activity GO:0004505 IEA
    identical protein binding GO:0042802 IEA
Biological Process
    protein homotetramerization GO:0051289 IEA
    tetrahydrobiopterin biosynthetic process GO:0006729 IEA
    transcription, DNA-templated GO:0006351 IEA
    protein heterooligomerization GO:0051291 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PCBD1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PCBD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PCBD1 is involved
Phenylalanine and tyrosine catabolism IEA Reactome

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