Gene description for REM2
Gene name RAS (RAD and GEM)-like GTP binding 2
Gene symbol REM2
Other names/aliases -
Species Bos taurus
 Database cross references - REM2
ExoCarta ExoCarta_531597
Vesiclepedia VP_531597
Entrez Gene 531597
 REM2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for REM2
Molecular Function
    GTPase activity GO:0003924 IEA
    calcium channel regulator activity GO:0005246 IEA
    GTP binding GO:0005525 IEA
Biological Process
    negative regulation of high voltage-gated calcium channel activity GO:1901842 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified REM2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for REM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which REM2 is involved
No pathways found





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