Gene description for SMTNL2
Gene name smoothelin-like 2
Gene symbol SMTNL2
Other names/aliases -
Species Bos taurus
 Database cross references - SMTNL2
ExoCarta ExoCarta_532143
Vesiclepedia VP_532143
Entrez Gene 532143
UniProt Q2KI85  
 SMTNL2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SMTNL2
Molecular Function
    tropomyosin binding GO:0005523 IEA
    protein phosphatase 1 binding GO:0008157 IEA
Biological Process
    actin cytoskeleton organization GO:0030036 IEA
    positive regulation of vasoconstriction GO:0045907 IEA
Subcellular Localization
    microtubule organizing center GO:0005815 IEA
    M band GO:0031430 IEA
    I band GO:0031674 IEA
    filamentous actin GO:0031941 IEA
 Experiment description of studies that identified SMTNL2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SMTNL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SMTNL2 is involved
No pathways found





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