Gene description for ING4
Gene name inhibitor of growth family, member 4
Gene symbol ING4
Other names/aliases -
Species Bos taurus
 Database cross references - ING4
ExoCarta ExoCarta_532483
Entrez Gene 532483
UniProt Q3T095  
 ING4 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ING4
Molecular Function
    transcription coactivator activity GO:0003713 ISS
    methylated histone binding GO:0035064 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    positive regulation of apoptotic process GO:0043065 ISS
    histone H3 acetylation GO:0043966 ISS
    histone H4-K8 acetylation GO:0043982 ISS
    DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 ISS
    histone H4-K12 acetylation GO:0043983 ISS
    negative regulation of cell proliferation GO:0008285 IEA
    histone H4-K16 acetylation GO:0043984 ISS
    cell cycle GO:0007049 IEA
    histone H4-K5 acetylation GO:0043981 ISS
    regulation of nucleic acid-templated transcription GO:1903506 ISS
Subcellular Localization
    nucleus GO:0005634 ISS
    histone acetyltransferase complex GO:0000123 ISS
 Experiment description of studies that identified ING4 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ING4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ING4 is involved
No pathways found





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