Gene description for FLOT1
Gene name flotillin 1
Gene symbol FLOT1
Other names/aliases -
Species Bos taurus
 Database cross references - FLOT1
ExoCarta ExoCarta_532573
Entrez Gene 532573
UniProt Q08DN8  
 FLOT1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FLOT1
Molecular Function
    protease binding GO:0002020 IEA
Biological Process
    establishment of protein localization to plasma membrane GO:0090002 IEA
    regulation of Rho protein signal transduction GO:0035023 IEA
    extracellular matrix disassembly GO:0022617 IEA
    axonogenesis GO:0007409 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    centriolar satellite GO:0034451 IEA
    melanosome GO:0042470 IEA
    flotillin complex GO:0016600 IEA
    lysosomal membrane GO:0005765 IEA
    COP9 signalosome GO:0008180 IEA
    focal adhesion GO:0005925 IEA
    endosome GO:0005768 ISS
    sarcolemma GO:0042383 IEA
 Experiment description of studies that identified FLOT1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FLOT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FLOT1 is involved
No pathways found





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