Gene description for FLOT1
Gene name flotillin 1
Gene symbol FLOT1
Other names/aliases -
Species Bos taurus
 Database cross references - FLOT1
ExoCarta ExoCarta_532573
Vesiclepedia VP_532573
Entrez Gene 532573
UniProt Q08DN8  
 FLOT1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FLOT1
Biological Process
    regulation of receptor internalization GO:0002090 IEA
    positive regulation of endocytosis GO:0045807 IEA
    protein kinase C signaling GO:0070528 IEA
    protein localization to plasma membrane GO:0072659 IEA
    positive regulation of cell junction assembly GO:1901890 IEA
    positive regulation of cell-cell adhesion mediated by cadherin GO:2000049 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified FLOT1 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FLOT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here