Gene description for CDC42
Gene name cell division cycle 42
Gene symbol CDC42
Other names/aliases -
Species Bos taurus
 Database cross references - CDC42
ExoCarta ExoCarta_532712
Entrez Gene 532712
UniProt Q2KJ93  
 CDC42 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CDC42
Molecular Function
    GTP binding GO:0005525 IEA
Biological Process
    nervous system development GO:0007399 IEA
    cell differentiation GO:0030154 IEA
    regulation of filopodium assembly GO:0051489 ISS
    regulation of attachment of spindle microtubules to kinetochore GO:0051988 ISS
    small GTPase mediated signal transduction GO:0007264 IEA
    positive regulation of substrate adhesion-dependent cell spreading GO:1900026 ISS
    positive regulation of cytokinesis GO:0032467 ISS
Subcellular Localization
    microtubule organizing center GO:0005815 IEA
    cytoplasm GO:0005737 IEA
    midbody GO:0030496 ISS
    membrane GO:0016020 ISS
    plasma membrane GO:0005886 IEA
    spindle midzone GO:0051233 ISS
    mitotic spindle GO:0072686 ISS
 Experiment description of studies that identified CDC42 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CDC42
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CDC42 is involved
No pathways found





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