Gene description for THOC5
Gene name THO complex 5
Gene symbol THOC5
Other names/aliases -
Species Bos taurus
 Database cross references - THOC5
ExoCarta ExoCarta_533001
Entrez Gene 533001
UniProt A4IFQ0  
 THOC5 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for THOC5
Molecular Function
    mRNA binding GO:0003729 IEA
Biological Process
    RNA splicing GO:0008380 IEA
    positive regulation of DNA-templated transcription, elongation GO:0032786 IEA
    stem cell division GO:0017145 IEA
    negative regulation of macrophage differentiation GO:0045650 IEA
    mRNA processing GO:0006397 IEA
    cell morphogenesis GO:0000902 IEA
    primitive hemopoiesis GO:0060215 ISS
    negative regulation of DNA damage checkpoint GO:2000002 IEA
    regulation of stem cell division GO:2000035 IEA
    monocyte differentiation GO:0030224 ISS
    regulation of mRNA export from nucleus GO:0010793 IEA
    viral mRNA export from host cell nucleus GO:0046784 IEA
    blastocyst development GO:0001824 IEA
Subcellular Localization
    THO complex part of transcription export complex GO:0000445 IEA
    nuclear speck GO:0016607 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified THOC5 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THOC5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which THOC5 is involved
No pathways found

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