Gene description for TSC1
Gene name tuberous sclerosis 1
Gene symbol TSC1
Other names/aliases -
Species Bos taurus
 Database cross references - TSC1
ExoCarta ExoCarta_533440
Vesiclepedia VP_533440
Entrez Gene 533440
 TSC1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TSC1
Biological Process
    negative regulation of cell population proliferation GO:0008285 IEA
    negative regulation of TOR signaling GO:0032007 IEA
    regulation of cell cycle GO:0051726 IEA
Subcellular Localization
    TSC1-TSC2 complex GO:0033596 IEA
 Experiment description of studies that identified TSC1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TSC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TSC1 is involved
No pathways found





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