Gene description for DDR2
Gene name discoidin domain receptor tyrosine kinase 2
Gene symbol DDR2
Other names/aliases -
Species Bos taurus
 Database cross references - DDR2
ExoCarta ExoCarta_533523
Vesiclepedia VP_533523
Entrez Gene 533523
 DDR2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DDR2
Molecular Function
    collagen binding GO:0005518 IEA
    ATP binding GO:0005524 IEA
    protein tyrosine kinase collagen receptor activity GO:0038062 IEA
Biological Process
    protein phosphorylation GO:0006468 IEA
    cell surface receptor protein tyrosine kinase signaling pathway GO:0007169 IEA
    multicellular organism development GO:0007275 IEA
    positive regulation of kinase activity GO:0033674 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    receptor complex GO:0043235 IEA
 Experiment description of studies that identified DDR2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DDR2 is involved
No pathways found





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