Gene description for PSPH
Gene name phosphoserine phosphatase
Gene symbol PSPH
Other names/aliases -
Species Bos taurus
 Database cross references - PSPH
ExoCarta ExoCarta_533630
Entrez Gene 533630
UniProt Q2KHU0  
 PSPH identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PSPH
Molecular Function
    magnesium ion binding GO:0000287 ISS
    protein homodimerization activity GO:0042803 IEA
    phosphoserine phosphatase activity GO:0004647 ISS
    calcium ion binding GO:0005509 ISS
Biological Process
    L-serine metabolic process GO:0006563 ISS
    L-serine biosynthetic process GO:0006564 IBA
    dephosphorylation GO:0016311 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified PSPH in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PSPH
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PSPH is involved
PathwayEvidenceSource
Serine biosynthesis IEA Reactome





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