Gene description for PSPH
Gene name phosphoserine phosphatase
Gene symbol PSPH
Other names/aliases -
Species Bos taurus
 Database cross references - PSPH
ExoCarta ExoCarta_533630
Entrez Gene 533630
UniProt Q2KHU0  
 PSPH identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PSPH
Molecular Function
    magnesium ion binding GO:0000287 ISS
    protein homodimerization activity GO:0042803 IEA
    phosphoserine phosphatase activity GO:0004647 ISS
    calcium ion binding GO:0005509 ISS
Biological Process
    L-serine metabolic process GO:0006563 ISS
    L-serine biosynthetic process GO:0006564 IBA
    dephosphorylation GO:0016311 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified PSPH in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PSPH
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PSPH is involved
PathwayEvidenceSource
Serine biosynthesis IEA Reactome





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