Gene description for IRAK1
Gene name	interleukin-1 receptor-associated kinase 1
Gene symbol	IRAK1
Other names/aliases	-
Species	Bos taurus
Database cross references - IRAK1
ExoCarta	ExoCarta_533953
Entrez Gene	533953
UniProt	Q2LGB3
IRAK1 identified in exosomes derived from the following tissue/cell type
Milk	23459212

Gene ontology annotations for IRAK1

Molecular Function     protein heterodimerization activity GO:0046982 IEA     interleukin-1 receptor binding GO:0005149 IEA     ATP binding GO:0005524 IEA     protein homodimerization activity GO:0042803 IEA     protein serine/threonine kinase activity GO:0004674 IEA Biological Process     toll-like receptor 2 signaling pathway GO:0034134 IEA     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IEA     protein autophosphorylation GO:0046777 IEA     protein oligomerization GO:0051259 IEA     negative regulation of NF-kappaB transcription factor activity GO:0032088 IEA     toll-like receptor 4 signaling pathway GO:0034142 IEA     innate immune response GO:0045087 IEA     regulation of cytokine-mediated signaling pathway GO:0001959 IEA     interleukin-1-mediated signaling pathway GO:0070498 IEA     activation of NF-kappaB-inducing kinase activity GO:0007250 IEA     lipopolysaccharide-mediated signaling pathway GO:0031663 IEA     positive regulation of NF-kappaB transcription factor activity GO:0051092 IEA     response to peptidoglycan GO:0032494 IEA Subcellular Localization     nucleus GO:0005634 IEA     lipid particle GO:0005811 ISS     cytoplasm GO:0005737 IEA