Gene description for CCDC22
Gene name coiled-coil domain containing 22
Gene symbol CCDC22
Other names/aliases -
Species Bos taurus
 Database cross references - CCDC22
ExoCarta ExoCarta_534246
Entrez Gene 534246
UniProt Q1RMI8  
 CCDC22 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CCDC22
Molecular Function
    cullin family protein binding GO:0097602 IEA
    molecular_function GO:0003674 ND
Biological Process
    Golgi to plasma membrane transport GO:0006893 IEA
    cellular copper ion homeostasis GO:0006878 IEA
    protein transport GO:0015031 IEA
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IEA
    cytoplasmic sequestering of NF-kappaB GO:0007253 IEA
    biological_process GO:0008150 ND
    positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:2000060 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
    endosome GO:0005768 IEA
 Experiment description of studies that identified CCDC22 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CCDC22
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CCDC22 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here