Gene description for CFL1
Gene name cofilin 1 (non-muscle)
Gene symbol CFL1
Other names/aliases -
Species Bos taurus
 Database cross references - CFL1
ExoCarta ExoCarta_534553
Entrez Gene 534553
UniProt Q5E9F7  
 CFL1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CFL1
Molecular Function
    actin binding GO:0003779 IEA
Biological Process
    response to virus GO:0009615 IEA
    regulation of cell morphogenesis GO:0022604 ISS
    neural fold formation GO:0001842 IEA
    protein phosphorylation GO:0006468 IEA
    establishment of cell polarity GO:0030010 IEA
    regulation of dendritic spine morphogenesis GO:0061001 IEA
    mitotic cytokinesis GO:0000281 IEA
    neural crest cell migration GO:0001755 IEA
    cytoskeleton organization GO:0007010 ISS
    positive regulation of actin filament depolymerization GO:0030836 IEA
    actin filament depolymerization GO:0030042 IEA
    response to amino acid GO:0043200 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    ruffle membrane GO:0032587 IEA
    nuclear matrix GO:0016363 IEA
    extracellular exosome GO:0070062 IEA
    cell-cell junction GO:0005911 IEA
    cortical actin cytoskeleton GO:0030864 IEA
    lamellipodium membrane GO:0031258 IEA
    focal adhesion GO:0005925 IEA
 Experiment description of studies that identified CFL1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CFL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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