Gene description for DSTYK
Gene name dual serine/threonine and tyrosine protein kinase
Gene symbol DSTYK
Other names/aliases RIPK5
Species Bos taurus
 Database cross references - DSTYK
ExoCarta ExoCarta_534684
Entrez Gene 534684
UniProt Q4TVR5  
 DSTYK identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DSTYK
Molecular Function
    protein tyrosine kinase activity GO:0004713 IEA
    ATP binding GO:0005524 IEA
    protein serine/threonine/tyrosine kinase activity GO:0004712 IEA
    protein serine/threonine kinase activity GO:0004674 IEA
Biological Process
    positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 ISS
    positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS
    peptidyl-tyrosine phosphorylation GO:0018108 IEA
    positive regulation of kinase activity GO:0033674 ISS
    cellular response to fibroblast growth factor stimulus GO:0044344 ISS
Subcellular Localization
    cell junction GO:0030054 IEA
    basolateral plasma membrane GO:0016323 ISS
    apical plasma membrane GO:0016324 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified DSTYK in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DSTYK
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DSTYK is involved
No pathways found





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