Gene description for GSN
Gene name gelsolin
Gene symbol GSN
Other names/aliases -
Species Bos taurus
 Database cross references - GSN
ExoCarta ExoCarta_535077
Entrez Gene 535077
UniProt Q3SX14  
 GSN identified in exosomes derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for GSN
Molecular Function
    calcium ion binding GO:0005509 IEA
    actin binding GO:0003779 IEA
Biological Process
    actin nucleation GO:0045010 IEA
    barbed-end actin filament capping GO:0051016 IEA
    actin filament severing GO:0051014 IEA
    cilium morphogenesis GO:0060271 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified GSN in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GSN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GSN is involved
No pathways found





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