Gene description for MDH1
Gene name malate dehydrogenase 1, NAD (soluble)
Gene symbol MDH1
Other names/aliases -
Species Bos taurus
 Database cross references - MDH1
ExoCarta ExoCarta_535182
Entrez Gene 535182
UniProt Q3T145  
 MDH1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MDH1
Molecular Function
    L-malate dehydrogenase activity GO:0030060 IEA
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    malate metabolic process GO:0006108 IEA
    tricarboxylic acid cycle GO:0006099 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 IEA
    centrosome GO:0005813 IEA
 Experiment description of studies that identified MDH1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MDH1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MDH1 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome





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