Gene description for ABCG2
Gene name ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
Gene symbol ABCG2
Other names/aliases -
Species Bos taurus
 Database cross references - ABCG2
ExoCarta ExoCarta_536203
Entrez Gene 536203
UniProt Q4GZT4  
 ABCG2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ABCG2
Molecular Function
    protein homodimerization activity GO:0042803 IEA
    ATPase activity, coupled to transmembrane movement of substances GO:0042626 IEA
    ATP binding GO:0005524 IEA
Biological Process
    transmembrane transport GO:0055085 IEA
    urate metabolic process GO:0046415 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    nucleoplasm GO:0005654 IEA
    mitochondrial membrane GO:0031966 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified ABCG2 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ABCG2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ABCG2 is involved
PathwayEvidenceSource
Abacavir transmembrane transport IEA Reactome
Iron uptake and transport IEA Reactome





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