Gene description for HECTD1
Gene name HECT domain containing E3 ubiquitin protein ligase 1
Gene symbol HECTD1
Other names/aliases -
Species Bos taurus
 Database cross references - HECTD1
ExoCarta ExoCarta_536240
Vesiclepedia VP_536240
Entrez Gene 536240
 HECTD1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HECTD1
Molecular Function
    protein binding GO:0005515 IEA
    metal ion binding GO:0046872 IEA
    ubiquitin protein ligase activity GO:0061630 IEA
Biological Process
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IEA
    anatomical structure development GO:0048856 IEA
    protein K63-linked ubiquitination GO:0070534 IEA
Subcellular Localization
    nuclear speck GO:0016607 IEA
 Experiment description of studies that identified HECTD1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HECTD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HECTD1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here