Gene description for DDAH1
Gene name dimethylarginine dimethylaminohydrolase 1
Gene symbol DDAH1
Other names/aliases -
Species Bos taurus
 Database cross references - DDAH1
ExoCarta ExoCarta_537391
Vesiclepedia VP_537391
Entrez Gene 537391
UniProt P56965  
 DDAH1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DDAH1
Molecular Function
    dimethylargininase activity GO:0016403 IEA
    amino acid binding GO:0016597 IEA
Biological Process
    citrulline metabolic process GO:0000052 IEA
    arginine metabolic process GO:0006525 IEA
    positive regulation of nitric oxide biosynthetic process GO:0045429 IEA
 Experiment description of studies that identified DDAH1 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDAH1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DDAH1 is involved
PathwayEvidenceSource
eNOS activation IEA Reactome
Metabolism IEA Reactome
Metabolism of nitric oxide: NOS3 activation and regulation IEA Reactome





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