Gene description for DDAH1
Gene name dimethylarginine dimethylaminohydrolase 1
Gene symbol DDAH1
Other names/aliases -
Species Bos taurus
 Database cross references - DDAH1
ExoCarta ExoCarta_537391
Entrez Gene 537391
UniProt P56965  
 DDAH1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DDAH1
Molecular Function
    zinc ion binding GO:0008270 IDA
    dimethylargininase activity GO:0016403 ISS
Biological Process
    citrulline metabolic process GO:0000052 ISS
    positive regulation of nitric oxide biosynthetic process GO:0045429 IDA
    protein nitrosylation GO:0017014 IDA
    regulation of systemic arterial blood pressure GO:0003073 IEA
    nitric oxide biosynthetic process GO:0006809 IDA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified DDAH1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DDAH1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DDAH1 is involved
No pathways found





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